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  • Autologous Chondrocyte Implantation
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    Autologous chondrocyte implantation repairs damaged cartilage with your own cultured cartilage cells.

    INFORMATIONSurgery Overview

    Surgery Time

    About 30 min

    Incision

    About 2 cm

    Anesthesia

    Local

    Walking

    Day after surgery

    Daily Life

    Discharged next day

    Showering

    After stitch removal

    Dangol Hospital logo

    M E A N I N G

    What Is Autologous Chondrocyte Implantation?

    Where bones meet at a joint, there is articular cartilage, which absorbs shock and keeps the joint moving smoothly.

    However, once this cartilage wears away, localized degenerative changes begin, and damaged cartilage cannot regenerate.

    In such cases, taking into account the extent of cartilage damage and the patient's physical condition, autologous chondrocyte implantation (ACI) may be performed: some of the patient's own healthy cartilage cells are harvested and implanted into the damaged area.

    In ACI, some of the patient's own healthy cartilage cells are harvested, multiplied several hundredfold in a special process, and then implanted into the damaged area.

    Because your own cartilage is used, recovery with healthy cartilage can be fast, and side effects and rejection reactions are rare.

    Surgeons performing knee surgery

    CASEWho Is a Candidate?

    For patients aged 15 to 55 with articular cartilage damage, who unlike older adults need to stay active after surgery, ACI is recommended over joint replacement, which lasts about 15–20 years. The cartilage defect must be between 2 and 15 cm² in size, and the cartilage next to the damaged area must be relatively healthy.

    TREATMENTHow Is the Surgery Performed?

    STEP 01

    A small amount of healthy cartilage is harvested arthroscopically from a part of the joint that is used little.

    STEP 02

    The harvested cartilage is sent to a cell processing facility and cultured for about 6 weeks. The 12–15 million successfully cultured cartilage cells are mixed with a fibrin adhesive and injected so that they settle into the damaged area.

    ADVANTAGEAdvantages of
    Chondrocyte Implantation

    • · Because it is done arthroscopically, the incision is small, there is less pain and recovery is fast.
    • · Your own cartilage tissue is used, so side effects and rejection reactions are rare.
    • · Once regenerated, the cartilage settles permanently, so there is no worry about implant lifespan as with joint replacement.
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